首先我打开wxpython的网站，下载了适合os x使用的包，装载、安装，一切都很顺利。
但是打开python，import wx的时候却报错了。

>>> import wx
Traceback (most recent call last):
  File "", line 1, in 
  File "/usr/local/lib/wxPython-unicode-2.8.12.1/lib/python2.7/site-packages/wx-2.8-mac-unicode/wx/__init__.py", line 45, in 
    from wx._core import *
  File "/usr/local/lib/wxPython-unicode-2.8.12.1/lib/python2.7/site-packages/wx-2.8-mac-unicode/wx/_core.py", line 4, in 
    import _core_
ImportError: /usr/local/lib/wxPython-unicode-2.8.12.1/lib/python2.7/site-packages/wx-2.8-mac-unicode/wx/_core_.so: no appropriate 64-bit architecture (see "man python" for running in 32-bit mode)

错误提示里让我们“man python”查看32位模式下运行的帮助。

64-BIT SUPPORT
     Versions 2.6 and 2.7 support 64-bit execution (which is on by default).

     Like the version of Python, the python command can select between 32 and 64-bit execution (when both are available).  Use:

           % defaults write com.apple.versioner.python Prefer-32-Bit -bool yes

     to make 32-bit execution the user default (using `/Library/Preferences/com.apple.versioner.python' will set the system-wide default).  The environment variable VERSIONER_PYTHON_PREFER_32_BIT can
     also be used (has precedence over the preference file):

           % export VERSIONER_PYTHON_PREFER_32_BIT=yes # Bourne-like shells
                or
           % setenv VERSIONER_PYTHON_PREFER_32_BIT yes # C-like shells

     Again, the preference setting and environmental variable applies to both python and pythonw.

很明确了。
我执行了

export VERSIONER_PYTHON_PREFER_32_BIT=yes

然后重新打开python
import wx
成功，可以使用了。
下面是个简单的测试

InternelpdeiMac:~ internelp$ python
Python 2.7.5 (default, Aug 25 2013, 00:04:04) 
[GCC 4.2.1 Compatible Apple LLVM 5.0 (clang-500.0.68)] on darwin
Type "help", "copyright", "credits" or "license" for more information.
>>> import wx
>>> app=wx.App()
>>> win=wx.Frame(None,title="wxPython Window")
>>> btn=wx.Button(win,label='Install wxPython')
>>> win.Show()
>>> app.MainLoop()

wxpython